Pancreatin

Pancreatin Tablets - Quadruple Strength (50) / Solgar Ref: SO/E2129
Pancreatin Tablets
Quadruple Strength, Providing Digestive Enzymes

DIRECTIONS FOR USE: As a food supplement for adults, one (1) tablet daily, preferably at mealtime, or as directed by a healthcare practitioner.

Each tablet provides:

Pancreatin (4X concentrate) 750mg
equivalent to 3000mg of whole pancreatin
Providing:

Protease 75,000 USP units
Amylase 75,000 USP units
Lipase 15,000 USP units
Tableted with these natural ingredients: vegetable cellulose, vegetable stearic acid, magnesium stearate.

This product is enteric coated for maximum utilization in the small intestine.

Sugar, salt and starch free.

50 Capsules.
Price: £8.45

Pancreatin
Pancreatin is an extract from the pancreas, a large gland that lies in the upper abdomen, behind the lower part of the stomach. The pancreas serves two major functions. One is to produce the hormones insulin and glucagon, which help regulate metabolism. The other is to produce pancreatic juice, a secretion delivered into the upper part of the small intestine (duodenum), where it aids digestion.
Pancreatin is a mixture of the fat dissolving enzyme, lipase, the protein enzymes such as protease, and those that break down carbohydrates like amylase. The enzymes in pancreatin may come from pork or beef. Pancreatic enzymes are not standardised, and contain a variety of enzymes, including trypsin, chymotrypsin, lipase, amylase, colipase, and ribonuclease.
These enzymes catalyze the hydrolysis of fats into glycerol and fatty acids, protein into proteoses and derived substances, and starch into dextrins and sugars.
Pancreatin tablets are used by people who are unable to digest food properly because of an insufficient amount of natural pancreatic secretions. This deficit may be caused by disorders of the pancreas, for example, cystic fibrosis or pancreatitis.
When malabsorption is due to reduced pancreatic function, improved digestion of food can lead to enhanced nutrient absorption, prevention of weight loss and diarrhoea, reduction of steatorrhea, and promotion of weight gain.
Enzymes work best when taken just before, during and immediately after a meal. When possible, swallow the pills whole. Do not chew.
Pancreatic insufficiency combined with pancreatic pain and endocrine pancreatic insufficiency are the leading symptoms of chronic pancreatitis. A number of studies have dealt with the problems of gastric acid inactivation of pancreatic enzyme preparations as well as their gastric emptying nonsimultaneously with the food. For this reason, commercial preparations of pancreatin (i.e. those not intended for prescription-only use) are normally in delayed-release tablets.
Excessive doses of pancreatin may result in gastrointestinal adverse effects, ie, nausea, vomiting, diarrhea, and abdominal cramps/pain. Very high doses have been reported to cause hyperuricosuria and hyperuricemia. Patients with a history of sensitivity to pork products, trypsin, pancrelipase, or pancreatin may develop allergic reactions.

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