L-Phenyalanine

L-Phenyalanine 500mg Vegicaps (50) / Solgar Ref: SO/E2200
L-Phenylalanine 500 mg Vegetable Capsules (Free Form)

SUITABLE FOR VEGANS - KOSHER

DIRECTIONS FOR USE: As a food supplement for adults, one (1) Vegetable Capsule daily with juice or water in between meals, or as directed by a healthcare practitioner.

Each Vegetable Capsule provides:

L-Phenylalanine 500 mg
Encapsulated with these natural ingredients: dibasic calcium phosphate, magnesium stearate.

Vegetable capsule shell: hydroxypropylmethyl cellulose.

CAUTION: PHENYLKETONURICS (PKU) - This product contains L-Phenylalanine.

Sugar, salt and starch free. Suitable for vegans.

50 x 500mg Vegicaps.
Price: £11.45

L-Phenylalanine
Phenylalanine is an essential amino acid that is normally converted to tyrosine in the body.
L-phenylalanine (LPA) serves as a building block for the various proteins that are produced in the body. L-phenylalanine can be converted to l-tyrosine and subsequently to l-dopa, noradrenaline, and adrenaline.
Phenylalanine is used to treated depression, menstrual cramps, Parkinson's disease (improves speech and rigidity), and vitiligo (a skin pigment disorder). Phenylalanine is part of certain hormones in the body which affect moods e.g., melanotropin and endorphins etc. Noradrenaline is believed to be in short supply in the brains of people who are depressed. By taking in extra phenylalanine, it is hoped the brain will make more noradrenaline. L-phenylalanine can promote high blood pressure in those predisposed to hypertension. Phenylalanine can promote the growth of existing malignant melanoma cells. L-phenylalanine may also be useful in the treatment of vitiligo.
Phenylalanine stimulates a particular hormone (cholecystokinin) in the body which causes suppression of the appetite. Phenylalanine can be used to form glucose in the body which is needed for energy production.
L-phenylalanine is found in most foods that contain protein such as beef, poultry, pork, fish, milk, yogurt, cheese, soy products (including soy protein isolate, soybean flour, and tofu), and certain nuts and seeds. Aspartame is also high in phenylalanine. Vegetables and juices contain small amounts of the free amino acid.
L-phenylalanine has been used in amounts up to 3.5 grams per day. Recommended dosages of phenylalanine vary depending on the health condition being treated. It's necessary to seek medical advice before supplementation. Supplements are recommended 15 to 30 minutes before meals.
Deficiencies can occur if the enzyme that converts phenylalanine to tyrosine is absent. Phenylketonuria (PKU), a rare metabolic disorder, occurs in people who are missing an enzyme that is needed to properly metabolize phenylalanine. Symptoms of PKU, which tend to appear between three and six months of age, include eczema, developmental delay, an abnormally small head, and hyperactivity. A deficiency in diet would only occur with an extremely low protein intake. Symptoms of phenylalanine deficiency may include confusion, emotional agitation, depression, decreased alertness, decreased memory, behavioural changes, decreased sexual interest, bloodshot eyes, and cataracts. If not corrected by supplemental dietary phenylalanine and tyrosine, the deficiency may lead to restricted weight gain and stunted growth, osteopenia, anaemia, alopecia, and even death.
Toxicity is rare in dietary intake but large amounts in supplement form may increase your blood pressure and cause headaches, nausea and heartburn. Large amounts of phenylalanine may also cause nerve damage. Toxicity symptoms include increased blood pressure and emotional agitation, insomnia, headaches, and tyrosine toxicity. Individuals with PKU and women who are lactating or pregnant should avoid supplementation. People with melanomas should also avoid Phenylalanine supplementation as it may stimulate the growth of this skin cancer. L-dopa competes with phenylalanine and should not be taken at the same time of day. Doses in excess of 5,000 mg a day may be toxic and can cause nerve damage.

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